Although genetic testing can benefit society in numerous ways, such as the diagnosis of vulnerabilities to inherited diseases and ancestry verification, it also has the precarious capability to become a tool in selecting a more favorable genetic makeup of an individuals and ultimately cloning humans. Genetic testing will depreciate our quality of life and may result in discrimination, invasion of privacy, and harmful gene therapy. In 1993 a pamphlet by National Heart, Lung, and Blood Institute was released heralding Gene Therapy. Although gene testing had been around and used for various procedures and breakthroughs, gene therapy had the potential to change the face of research, as we knew it. Medical scientists had finally found a way to manipulate human genes and possibly change faulty genes in an attempt to replace them in order to treat and cure diseases. Thus the first patients were treated at the National Institutes of Health (NIH) in Bethesda, Maryland.
Two years after receiving their last infusions of generally altered cells to boost their weakened immune systems; the first patients ever to undergo gene therapy are still healthy and benefiting from the treatment. According to a historic research paper published in Science on October 19, 1995, the two girls still have white blood cells bearing copies of the replacement ADA gene. Patient One, whose health improved significantly following gene therapy, has maintained a normal white blood cell count as well as measurable levels of the ADA enzyme, which was almost nonexistent prior to the treatment. The process was less efficient in Patient Two. Only about one percent of her T cells incorporated the virus into their DNA. In another case, an 18-year-old Arizona man with a rare metabolic disease participated in a controversial experiment which marked the first death attributed to gene therapy.
Jesse Gelsinger, a high school graduate who episodically suffered from a serious genetic disorder that often leads to coma and death in childhood, died Sept. 17, 1999 after undergoing an experimental therapy administered at the University of Pennsylvania in Philadelphia. Thousands of U. S.
patients have been treated with various kinds of gene therapy, an experimental technique in which doctors use live viruses and other means to transport potentially therapeutic genes into the body just as Gelsinger was. Gelsinger suffered from Ornithine Transcarbamylase (OTC) deficiency, a genetic disorder that affects mostly boys. The disease blocks the body's ability to break down ammonia, a normal byproduct of metabolism, and often causes death soon after birth. As a result the FDA initiated proceeding that could have prevented the University of Pennsylvania gene therapy researcher, James Wilson, from testing experimental drugs or products on human subjects in this country. He repeatedly or deliberately violated regulations governing the proper conduct of clinical studies.
How many people can say that they would want someone they trusted to perform a procedure that ultimately takes the research into his or her own hands and may result in death? It stirs up not only ethical issues but issues such as prejudice and discrimination. Hypothetically say there are some doctors who will decide to take a risk with your gene therapy and either add or remove something experimental. What would be the purpose of the FDA placing the guidelines that they have for gene therapy there in the first place? Research doctors are the professionals expected to do everything according to set standards and guidelines when interacting with live human patients. Although the hope for gene therapy is to eradicate inherited diseases, the potential for gross misuse is great. Procedures may progress to the unethical practice of choosing the eye color and physical characteristics of a child eventually leading to discrimination and prejudice. I believe that there is a reason for the different diseases and ailments in the world today.
If there were never anything wrong with humans other than the occasional cold, I believe man would invent something which could develop into something as deadly as AIDS-which was developed in a lab. If faced with the choice of genetic testing for a disease I would not do it. I would try every other method before trying it. I don't want to say what my way is the only way or the right way but if I'm given the wrong test, or a researcher decides to do his own thing and not follow procedure, or maybe I'm injected with the wrong thing and I end up with something like cancer then I have to live with that, or die if that is a result. Genetic testing will depreciate our quality of life and may result in discrimination, invasion of privacy, and harmful gene therapy. It can benefit society in numerous ways, such as the diagnosis of vulnerabilities to inherited diseases and ancestry verification.
Genetic Testing also has the precarious capability to become a tool in selecting a more favorable genetic makeup of an individuals and ultimately cloning humans.
Following example essays might be related to your topic and facilitate your research and writing.
- Genetic Disorder Gene Therapy 2000
2,251 wordsBrad Miller Ms. Cheryl Weatherly English Composition and Research 2 July 2000 Gene-therapy: How will it Change the Future of Genetic Disorders Ten years ago researchers from the U. S. , Britain, France, Germany, Japan and China sat down and began developing the most important map ever made. Instead ...
- Gene Therapy Genes One Web
1,728 wordsGenetic disorders have been plaguing people for ages and causing fatalities. However, with new information and research, and something called gene therapy, hope now exists for these unfortunate individuals. Gene therapy is a technique for correcting defective genes responsible for disease developmen...
- Gene Therapy Patient Cells Vivo
410 wordsGene therapyGenetherapy Gene Therapy Gene therapy is the use of genes and the techniques of genetic engineering in the treatment of a genetic disorder or chronic disease. There are many techniques of gene therapy. The two basic methods are called in vivo and ex vivo gene therapy. The in vivo method ...
Still cannot find the paper you need? Buy essay or research paper tailored exactly to your instructions and demands -- original, written from scratch for you!
Free essay examples, how to write essay on Argumentative Essay On Genetic Testing
Research On Genetic Testing
Genetic Testing is a part of medical testing that comprises of testing and identifying any significant changes in genes, proteins or chromosomes. Due to advances in technology related to medical domain, several tests advanced have been developed. Genetic testing is used in situations where there is possibility of inheriting diseases, prenatal screening, carrier testing, screening for newly born babies etc.
Research on Genetic Testing
Genetics is a branch of medical science that focuses on human features (for instance eye color) that are passed on to children from their parents through genes. Genetic testing is a testing process used in medical field to figure out deviation known as mutation in an individual’s genes or chromosomes. Currently more than 1,000 genetic testing methods have been developed. Results obtained from genetic testing depicts the presence or absence of genetic conditions and also shows if a person have any chances of acquiring or passing on a particular genetic disease.
Methods used for genetic testing
There are three different methods that are used for genetic testing process. They are described as follows:
- Molecular genetic tests: These tests study individual genes or short lengths of DNA to recognize varieties or transformations that prompt a hereditary issue.
- Chromosomal genetic tests: These tests break down entire chromosomes or long lengths of DNA to check whether there are expansive hereditary changes, for example, an additional duplicate of a chromosome, that cause a hereditary condition.
- Biochemical genetic tests: This particular test studies the sum or movement level of proteins; variations from the norm in either can show changes to the DNA that outcome in a hereditary issue.
Genetic testing is solely dependant on the person who wants to get it done. Since testing has advantages and also confinements and dangers, the choice about whether to be tried is an individual and complex one. A geneticist or hereditary advocate can help by giving data about the upsides and downsides of the test and examining the social and emotional parts of testing.
The conspicuous advantage of genetic testing is the chance for a superior comprehension of one's danger for a certain illness. Testing is not immaculate, but rather it can frequently help one to settle on choices about his / her well being.